Yale Center for Clinical Investigation
2 Church St. South
New Haven, CT 06519
Tel: 203.785.3482
Fax: 203.737.2480
ycci@yale.edu
Our mission is to facilitate NIH-funded adult and pediatric research projects. To this end, Core Research Services provide an investigator with access to selected analyses and procedures that might otherwise be unavailable or too expensive. Core Research Services are funded by NIH but designed by individual organizations. The Cores can change functions to match current research projects.
Analysis can begin at the patient's bedside. We offer point-of-care glucose (CLIA license), lactate and ethanol measurements. In addition, investigators can take advantage of bedside indirect calorimetry instrumentation. The inpatient facility is connected to the YNHH sample transport system which enables routine chemistries to reach Laboratory Medicine quickly.
All of this is supported by our own laboratory facilities to measure a variety of hormones, substrates, and cytokines.
Hours of operation: Monday – Friday (7:30am - 5pm)
In addition, the lab is usually open evenings 2-3 times each week and one weekend each month.
Contact:
Mikhail Smolgovsky, Processing
EP 10-611
Phone: (203) 785-6248
mikail.smolgovsky@yale.edu
A large facility capable of analyzing a variety of hormones utilizing RIA, IRMA, and ELISA techniques. Support focuses on assays not readily available in clinical laboratories or large batches of samples too expensive to send to routine hospital facilities.
Contact: 785-4178 Location: LMP 1088
An automated laboratory capable of measuring most routine substrates and clinical enzymes utilizing an Alfa-Wasserman ACE analyzer. Also suited to automating the measurement of research compounds using UV/VIS spectrophotometry.
Contact:
Jennifer Morgen, Substrates
HRT 519
Phone: (203) 785-5558
jennifer.morgen@yale.edu
Our newest core is capable of analyzing most cytokines and tissue markers using a UV/VIS plate reader. The analysis kits for many newly discovered hormones also utilize the ELISA technique making this an important resource to investigators.
Contact:
Christine Simpson, ELISA
LMP 1091
Phone: (203) 785-5452
christine.simpson@yale.edu
A small highly specialized area focusing on plasma catecholamine measurements and plasma free amino acid chromatography.
Contact: 785-4422 Location: LMP 1091
The Magnetic Resonance Research Center (MRRC) in collaboration with the YCCI provides supported access to this MRI resource. All systems have state-of-the-art electronics capable of performing the full range of MRS and MRI sequences including: 13C, 31P, and 1H MRS; spectral eliciting; short echo acquisition; and 3/4D spectroscopic imaging. The YCCI also provides nursing support and sample processing to facilitate patient safety and data collection.
This is a resource for investigators which provides even novice investigators with supported access to the Keck Lab at Yale, a state-of-the-art Affymetrix facility. This collaboration provides investigators with the following benefits:
Contact:
Keck, Proteomics Contact
Myron Crawford
300 George Street, Room 2104
Phone: (203) 737-2635
myron.crawford@yale.eduKeck, Genomics Contact
John Flory, PhD
300 George Street, Room 2128C
Phone: (203) 737-2209
john.flory@yale.edu