Yale School of Medicine

Yale Center for Clinical Investigation

Yale Center for Clinical Investigation

Yale Center for Clinical Investigation
2 Church St. South
New Haven, CT 06519
Tel: 203.785.3482
Fax: 203.737.2480
ycci@yale.edu

Erik M. Shapiro, PhD

Erik Shapiro

Assistant Professor of Diagnostic Radiology

1995 BS State University of New York at Binghamton, Chemistry
1997 MS University of Pennsylvania, Chemistry
2001 PhD University of Pennsylvania, Chemistry
2001-2004 Post-doc National Institutes of Health, Molecular Imaging

Positions

1994-1995  Research Assistant, Laboratory of Dr. Susan L. Bane, Department of Chemistry, State University of New York at Binghamton
1995-1996 Research Assistant, Laboratory of Dr. Phil A. Rea, Department of Biology, University of Pennsylvania
1996-1997 M.S. Student, Laboratory of Dr. Stanley J. Opella, Department of Chemistry, University of Pennsylvania
1998-2001 Ph.D. Student, Laboratory of Dr. John S. Leigh, Department of Radiology, University of Pennsylvania
2001-2004 Postdoctoral Fellow, Laboratory of Dr. Alan P. Koretsky, National Institutes of Health
2005-2006 Assistant Professor, Department of Radiology and The Helen and Martin Kimmel Center for Stem Cell Biology, New York University School of Medicine
2006 Assistant Professor, Department of Diagnostic Radiology, Yale University School of Medicine

Honors

1995 Graduate Fellowship in Structural and Molecular Genetic Studies, Plant Science Institute, University of Pennsylvania
1996 Phi Lambda Upsilon Chemistry Honor Society, President 1996-1997
2000 Young Investigator’s Award, Osteoarthritis Research Society International
2004 Fellow’s Award for Research Excellence, National Institutes of Health
2005 Young Investigator’s Award Finalist, International Society for Magnetic Resonance in Medicine

Patent

United States Patent # 6,836,114 - Pulse Imaging Sequences and Methods for T1ρ-Weighted MRI.

Publications

  • Shapiro, E.M., Gonzalez-Perez, O., Garcia-Verdugo, J.M.,  Alvarez-Buylla, A., Koretsky, A.P., Magnetic resonance imaging of the migration of neuronal precursors generated in the adult rodent brain, NeuroImage, 32(3), 1150-1157 (2006).
  • Rodriguez, O., Fricke, S., Chien, C., Dettin, L., VanMeter, J., Shapiro, E.M., Dai., H., Casimiro, M., Ileva, L., Dagata, J., Johnson, M., Koretsky, A.P., Albanese, C., Contrast-enhanced in vivo imaging of breast andprostate cancer cells by MRI, Cell Cycle, 5(1), 113-119 (2006).
  • Shapiro, E.M., Sharer, K., Skrtic, S., Koretsky, A.P., In vivo detection of single cells by MRI, Magnetic Resonance in Medicine, 55, 242-249 (2005).
  • Shapiro, E.M., Skrtic, S., Koretsky, A.P., Sizing it up: Cellular MRI using micron sized iron oxide particles, Magnetic Resonance in Medicine, 53, 329-338 (2005).
  • Himmelreich, U., Weber, R., Ramos-Cabrer, P., Wegener, S., Kandal, K., Shapiro, E.M., Koretsky, A.P., Hoehn, M., Improved stem cell MR detectability in animal models by modification of the inhalation gas, Molecular Imaging, 4(2) (2005).
  • Shapiro, E.M., Skrtic, S., Hill, J.M., Dunbar, C.E., Koretsky, A.P., MRI detection of single particles for molecular and cellular imaging, Proceedings of the National Academy of Sciences, USA, 191(30), 1389-1395  (2004).
  • Wheaton, A.J., Borthakur, A., Shapiro, E.M., Regatte, R.R., Akella, S.V.S., Kneeland, J.B., Reddy, R., Proteoglycan loss in human knee cartilage: Quantitation with sodium MR imaging – Feasibility Study, Radiology, 231, 900-905 (2004).
  • Hinds, K.A., Hill, J.M., Shapiro, E.M., Silva, A.C., Varney, T.R., Combs, C.A., Balaban, R.S., Koretsky, A.P., Dunbar, C.E., Highly efficient endosomal labelling of progenitor and stem cells with large magnetic particles allows magnetic resonance imaging of single cells, Blood, 102(3), 867-872 (2003).
  • Borthakur, A., Shapiro, E.M., Akella, S.V.S., Gougoutas, A., Kneeland, J.B., Reddy, R., Quantifying sodium in the human wrist in vivo using MRI, Radiology, 224, 598-602 (2002).
  • Shapiro, E.M., Borthakur, A., Shapiro, M.J., Reddy, R., and Leigh, J.S., Fast MR imaging of RF heating via phase difference mapping, Magnetic Resonance in Medicine, 47, 492-498 (2002).
  • Shapiro, E.M., Borthakur, A., Gougoutas, A. and Reddy, R., 23Na MRI accurately measures fixed charge density in articular cartilage, Magnetic Resonance in Medicine, 47, 284-291 (2002).