Peter Morgan, MD

Mentor

Robert Malison, MD

Project Description

Dr. Morgan’s research focuses on the effects of abstinence-related sleep deficits on cocaine relapse through extensive sleep physiology studies on cocaine-abstinent users in a sleep lab. He has completed a study that examines the effect of prolonged abstinence from cocaine on sleep and procedural learning in cocaine users and alcohol users. He is beginning projects looking at GABA levels in persons with insomnia and depression and the relationship between sleep and learning. The research is progressing according to the timeline. Dr. Malison reports that Dr. Morgan continues to be a highly productive researcher, successfully completing studies in a timely manner, having manuscripts published and successfully competing for grant stupport. He was selected as presenter for the Society for Neuroscience 2007 mini-symposium on Sleep and Drug Abuse.

Publications

1. Peter T. Morgan, Edward F. Pace-Schott, Zakir H. Sahul, Vladimir Coric, Robert Stickgold, Robert T. Malison. “Sleep, sleep-dependent procedural learning and vigilance in chronic cocaine users: evidence for occult insomnia”, Drug and Alcohol Dependence, 82:238-249, 2006.
2. W.J. Lynch, A. Sughondhabirom, B. Pittman, R. Gueorguieva, D. Joshua, P. Morgan, V. Coric, and R. T. Malison, “A paradigm to investigate the regulation of cocaine self-administration in human cocaine users: a randomized trial”, Psychopharmacology, 185: 306-314, 2006.
3. Rasmon Kalayasiri, M.D., Atapol Sughondhabirom, M.D., Ralitza Gueorguieva, Ph.D., Vladimir Coric, M.D., Wendy Lynch, Ph.D., Peter T. Morgan M.D. Ph.D., Joseph Cubells, M.D. Ph.D., Robert T. Malison, M.D. “Self-Reported Paranoia during “Binge” Cocaine Self-Administration in Humans”. Pharmacology, Biochemistry and Behavior, 83:249-256, 2006.
4. Peter T. Morgan. “Treatment resistant depression: response to low-dose transdermal but not oral selegiline”. Journal of Clinical Psychopharmacology, in press for June 2007.

Source(s) of Support

NIH Yale K12 Clinical Research
Training Program
5th year