Richard G. Kibbey, MD, PhD

Associate Research Scientist in Medicine (Endocrinology)

1987-1991	BS, Honors	Trinity University, San Antonio, TX, Biochemistry
1987-1991	BA	Trinity University, San Antonio, TX, Music
1992-2000	MD	University of Texas Southwestern Medical School, Dallas, TX
1992-2000	PhD	University of Texas Southwestern Medical School, Dallas, TX, Molecular Biophysics
2000-2002	Intern/Res.	Yale University School of Medicine, New Haven, CT, Internal Medicine

Positions

2002-2005	Clinical and Research Fellow, Section of Endocrinology, Department of Internal Medicine, Yale University, School of Medicine, New Haven, CT
2005-pres	Associate Research Scientist, Section of Endocrinology, Department of Internal Medicine, Yale University, School of Medicine
2005-pres	Endocrinology Consultant, Yale University Health Services, New Haven, CT

Honors

1991	BS in Biochemistry cum laude with University Honors
1991	BA in Music cum laude
1987-91	Deans List
1990-91	Blue Key University Honor Society
1987-91	President’s Academic Scholarship
1991	Winner of the Outstanding Presentation, Baylor Univ. Undergraduate Research Symposium
1993	Medical Student Research forum Finalist
1994-98	NIH Biophysics Training Grant
1997	Graduate Student Research Forum Finalist
1997	Sigma Xi Research Forum Finalist
1998	NIH Travel Award for Keystone Symposium (Specificity in Signal Transduction)
1999-2000	Merck Scholar
2004	American Diabetes Association Travel Grant

Professional Memberships

1993-pres	American Association for Advancement of Science
2005-2006	American Association of Clinical Endocrinologists
2006-pres	American Diabetes Association

Publications

• Bushey MM, Kurtin WE, Kibbey RG, Fintschenko Y, (1992) An Examination of the Bilirubin-Bile Salt System by MECC, Abstracts of American Chemical Society 204(1)136-Anyl
• Harman AD, Kibbey RG, Sablik MA, Fintschenko Y, Kurtin WE, Bushey MM. (1993) Micellar electrokinetic capillary chromatography analysis of the behavior of bilirubin in micellar solutions. J. Chromatography, 652:525-533
• Gierasch LM, Landry SJ, Maxwell J, Scott T, Triplett TL, Zheng N, Bansal A, Kibbey R (1993) Using peptides to explore how proteins are folded and sorted in vivo. Abstract, Keystone Symposia, J.Cellular Biochem. S17C:210
• Kibbey RG, Rizo J, Gierasch LM, Anderson RGW (1996) The internalization motif of the LDL receptor binds to clathrin coat proteins in a reverse turn conformation. Abstract, American Society for Cell Biology, Mol. Cell. Biol. 7S: 81a
• Kibbey, RG, Rizo J, Gierasch LM., Anderson RGW (1998) The LDL receptor clustering motif interacts with the clathrin terminal domain in a reverse turn conformation. J. Cell. Biol. 142:59-97
• Kibbey, RG,  Romanelli, AJ, Lepine, RL, Cline, GW, Shulman, GI, (2004) A Potential Role for Mitochondrial GTP Linking Mitochondrial Metabolism with Insulin Secretion, Diabetes 53(S2) A76
• Cline, GW, LePine, RL, Papas, KK, Kibbey, RG, Shulman, GI, (2004), 13C-NMR isopotomer analysis of anaplerotic pathways in INS-1 cells, J Biol Chem 279(43): 44370-5
• Kibbey, RG, Pongratz, RL, Romanelli, AJ, Cline, GW, and Shulman,(2005) GI Mitochondrial GTP Regulates Glucose Stimulated Insulin Secretion, Abstract, Keystone Symposia: Diabetes Mellitus J3(52):220
• Pongratz, RL, Kibbey, RG, Cline, GW (2005) Evidence for Different Roles of Cytosolic and Mitochondrial Malic Enzyme Isoforms in Control of Insulin Secretion, Diabetes, 54(S1):A43
• Pongratz, RL, Kibbey, RG, Shulman, GI, Cline, GW (2007) Cytosolic and Mitochondrial Malic Enzyme Isoforms Differentially Control Insulin Secretion, J. Biol. Chem., 282(1): 200-207
• Kibbey, RG, Pongratz, RL, Romanelli, AJ, Wollheim, CB, Cline, GW, Shulman, GI, (2007) Mitochondrial GTP Regulates Glucose-Stimulated Insulin Secretion, Cell Metabolism 5:253-64.

Theses

• Kibbey, RG (1991) Solubility of Unconjugated Bilirubin in Bile Salt Solutions: Analysis by Micellar Electrokinetic Capillary Chromatography, Undergraduate Honors Thesis, Trinity University, Department of Chemistry and Biochemistry, San Antonio, TX
• Kibbey, RG, (1998) The LDL Receptor Clustering Motif Interacts with the Clathrin Lattice: An analysis using Nuclear Magnetic Resonance Ph.D. Thesis, Molecular Biophysics, UT Southwestern Medical Center, Dallas, TX

Recent Meeting Abstracts

• Pongratz, RL, Kibbey, RG, Cline, GW, 13C isotopomer analysis of impaired insulin secretion following siRNA knockdown of cytosolic and mitochondrial malic enzyme isoforms in INS-1 cells. Keystone Symposia 2006
• Kibbey, RG, Pongratz, RL, Romanelli AJ, Cline GW, and Shulman, GI Mitochondrial GTP Regulates Insulin Secretion by Controlling Mitochondrial Calcium Cycling. Keystone Symposia 2006
• Romanelli, AJ, Kibbey, RG, Cline GW, Ferguson, JA, Quantitation of Cellular Redox Intermediates and Nucleotide Phosphates in Cultured Cells, 54th American Society for Mass Spectroscopy Conference 2006
• Mason, GF, Watzl, J, Gomex, RG, Guidone, E, Sanacora, G, George, T, Inzucchi, S, Kibbey, RG, Shulman, G, Krystal, J, Rothman, D, O’Malley, S Acute Nicotine Increases Occipital Cortical GABA Levels, Research Society on Alcoholism 2006