Yale School of Medicine

Yale Center for Clinical Investigation

Yale Center for Clinical Investigation

Yale Center for Clinical Investigation
2 Church St. South
New Haven, CT 06519
Tel: 203.785.3482
Fax: 203.737.2480
ycci@yale.edu

Marsha Kathleen Guess, MD

Marsha Guess

Assistant Professor of Obstetrics, Gynecology, and Reproductive Sciences

1990 B.S. Howard University, Microbiology
1997 M.D. University of California at Los Angeles, Medicine
2006 M.S. The Albert Einstein College of Medicine, Clinical Research Methods
     

Positions

1997 – 2001 Intern and Resident in Obstetrics & Gynecology,The University of California at Los Angeles, Los Angeles, CA
2001 – 2004 Clinical Fellow, Division of Urogynecology and Reconstructive Pelvic Surgery, Albert Einstein College of Medicine, Department of Obstetrics & Gynecology and Women’s Health, Bronx, NY
1991-1992 Clinical Research Associate I, Alpha Therapeutic Corporation, Los Angeles, CA
1992-1993 Clinical Research Associate II, Alpha Therapeutic Corporation, Los Angeles, CA
2000-2001 Chief Resident in Obstetrics & Gynecology, The University of California at Los Angeles, Los Angeles, CA
2001-2004 Instructor, Albert Einstein College of Medicine, Department of Obstetrics & Gynecology and Women’s Health, Bronx, NY
2004-2006 Assistant Professor, Albert Einstein College of Medicine, Department of Obstetrics & Gynecology and Women’s Health, Bronx, NY
2005-2006 Assistant Professor, Albert Einstein College of Medicine, Department of Urology, Bronx, NY
2006 –  Assistant Professor, Yale University School of Medicine, Department of Obstetrics and Gynecology & Reproductive Sciences, New Haven, CT

Honors

1994 The Harvard AIDS Institute Student Training Fellowship
1995 The Ciba-Geigy Award for Outstanding Community Service
1995 The 95th Street School Award for Dedication and Commitment to Education
1995 Rebecca Lee M.D. Scholarship 
1996 The Center of Excellence Minority Student Fellowship
1997 The GATE Pharmaceuticals’ Outstanding Medical Student Award
1998 The Larry Evertson Award for Best First Year Resident in OB/GYN
2001 The Ortho-McNeil Award for Outstanding Resident Research Paper
2002 – 2006 Division of Equity in Women’s and Perinatal Health Scholar
2004 The Bronx-Lebanon Hospital Resident Teaching Award
2006 Master of Science Degree with Distinction

Publications

Peer - reviewed original research

  • Connell K, Guess MK, LaCombe J, Powers K, Lazarou G, Mikhail MS. Evaluation of the Role of Pudendal Nerve Integrity in Female Sexual Function Using Non-invasive Techniques.  Am J Obstet Gynecol. 2005; 192: 1712–7.
  • Connell K, Guess MK, Bleustein CB, Powers K, Lazarou G, Mikhail MS, Melman A. Effects of Aging on Neurological Function of the Female Genitalia. Int J Impot Res.  2005; 17: 63–70.
  • Bensinger G, Lind L, Lesser M, Guess M, Winkler A.  Abdominal Sacral Suspensions: Analysis of complications using permanent mesh. Am J Obstet Gynecol. 2005;193:2094-8.
  • Guess MK, Connell KA, Schrader SM, Reutman SR, Wang A, La Combe J, Toennis C, Melman A, Mikhail M.  Genital sensation & sexual function in female cyclists and runners: Are your feet safer than your seat?  J Sex Med 2006; 3:1018–1027.

Editorials, Reviews, Chapters, Books

  • Rapkin AJ, Guess MK. Approach to the Patient with Pelvic Pain. In: Women’s Health, Principles and Clinical Practice, 1st edition, DeCherney A, M.D., Pregler J, M.D., B.C. Decker 2002.
  • Coleman JC, Guess MK, Rahimian J. Hyperprolactinemia. In: Women’s Health Principles and Clinical Practice, 1st edition, DeCherney A, M.D., Pregler J, M.D., B.C. Decker Inc. 2002.
  • Guess, MK, Andrew DE, Gaglardi CL, Emmi AM.  Hirsutism. In: Current Diagnosis and Treatment, Obstetric & Gynecologic, 9th edition, DeCherney A, Nathan L, The McGraw-Hill Companies 2003.
  • Heiman JR, Guess MK, Connell K, Melman A, Hyde JS, Segraves RT, Wyllie MG. Standards for Clinical Trials in Sexual Dysfunctions of Women: Research Designs and Outcomes Assessment.  In: Sexual Medicine: Sexual Dysfunctions in Men and Women, edited by T.F. Lue, R. Basson, R. Rosen, F. Giuliano, S. Khoury, F. Montorsi, Health Publications, Paris 2004.
  • Heiman JR, Guess MK, Connell K, Melman A, Hyde JS, Segraves RT, Wyllie MG. Standards for clinical trials in sexual dysfunctions of women: research designs and outcomes assessment.  J Sex Med. 2004; 1:92-7.
  • Wang A, Guess MK, Connell K, Powers K, Lazarou G, Mikhail M.  Fecal incontinence: a review of prevalence and obstetric risk factors. Int Urogynecol J Pelvic Floor Dysfunct. 2006;17:253-60.
  • Guess, MK, Andrew DE, Gaglardi CL, Emmi AM.  Hirsutism. In: Current Diagnosis and Treatment, Obstetric & Gynecologic, 10th edition, DeCherney AH, Nathan L, Goodwin TM, Laufer N. The McGraw-Hill Companies 2007.

Research Funding

Active

Vaginal Smooth Muscle Function in Pelvic Organ Prolapse

NIH Clinical and Translational Sciences Award         03/01/07 – 08/30/08
This project will explore the rates of vaginal smooth muscle cell proliferation and apoptosis as possible mechanims for pelvic organ prolapse in women
Principal Investigator: Marsha K. Guess

Completed

Smooth Muscle Differential Tissue Function & Diabetes

Urology 3 P01 DK 60037-03S1 Melman (PI)             07/01/05 – 06/30/06
NIH/NIDDK Research Supplement for Underrepresented Minorities

This grant provides salary support to translate techniques used in the Urology basic science laboratory to extend the focus to explore alterations in smooth muscle in lower urogenital pathology in women. 
Principal Investigator: Arnold Melman

Women’s Reproductive Health: Are Saddle Pressure and Cycling Duration Occupational Hazards?

Centers for Disease Control
National Institute of Occupational Safety and Health                        07/01/03 – 07/01/04

The goal of this project was to investigate the relationship between frequent and/or endurance cycling on female genital neurological and sexual function.
Principal Investigator: Marsha K. Guess