Karen B. Dorsey, MD

Instructor in Pediatrics (General Pediatrics)

1994	BA	University of Virginia, Spanish Language
1998	MD	Washington University School of Medicine
2006	PhD	Yale University School of Medicine, Investigative Medicine

Positions

1998-1999	Intern (Pediatrics) –Children’s Hospital of New York, New York Presbyterian Hospital, New York
1999-2001	Resident (Pediatrics) – Children’s Hospital of New York, New York Presbyterian Hospital, New York
2001-2003	Robert Wood Johnson Clinical Scholars Program, Yale University, New Haven
2003-2006	Fellow, Investigative Medicine Program, Yale University School of Medicine, New Haven
2006-2007	Instructor, Department of Pediatrics, Yale University School of Medicine, New Haven

Publications

• Compton WM, Cotler LB, Dorsey KB, Spitznagel EL, Mayer DE. Structured and semi-structured assessment of ICD-10 substance dependence disorders: CIDI-SAM vs. SCAN. International Journal of Methods in Psychiatric Research 6:285-293, 1996.
• Compton WM, Cotler LB, Dorsey KB, Spitznagel EL, Mayer DE. Comparing assessment of DSM-IV substance abuse disorders using CIDI-SAM and SCAN. Drug and Alcohol Dependence 41(3):179-187, 1996.
• Davis DA, Dorsey KB, Wingfield DT, Stahl ST, Kaufman S, Fales HM, Levine RL. Regulation of HIV-1 protease activity through cysteine modification. Biochemistry 35(7): 2482-2488, 1996.
• Dorsey KB, Wells C, Krumholz HM, Concato J. Diagnosis, evaluation, and treatment of obese children in practice.  Archives of Pediatric and Adolescent Medicine. 159(7): 632-8, 2005 Jul.

Research Funding

Current

Metabolic Effects of Differential Organ Growth Rates

HD 042187, Dympna Gallagher (PI)
NICHD – Research Supplement to Promote Diversity in Health Related Research
Physical Activity and Body Composition       $189,868         9/2006 to 8/2008                     80%
The overall goal of this project is to determine the relationship between physical activity levels and relative distribution of fat mass assessed using the mass of organ/tissue compartments and activity levels measured from direct motion monitoring (for 7 consecutive days) in a sample of Latino, African American, Caucasian and Asian 8 to 11 year old children; and, with a series of two periods of measurement to assess the relationship between change in activity levels and changes in body composition during one year of growth and pubertal development.
Role: Supplemental Research Project PI.

1UL1RR024139-01, Robert S. Sherwin (PI), Clinical and Translational Science Award (CTSA)
CTSA Scholar’s Award                       $30,000           3/2007 to 9/2008         Project Support
The goal of this project is to describe the impact of physical fitness measured by indirect calorimetry during exercise on the relationship between physical activity measured by accelerometer and body fat measured by magnetic resonance imaging in a cohort of 7 to 11 year old children.
Role: CTSA Scholar, and project PI.

Past

RR017648 Eugene Shapiro (PI)    $ 374,625     9/1/2003 – 6/30/2006          90%
NCRR
Mentored Clinical Research Scholar Award (K-12 Award)
The overall goal was to develop novel methods of describing and comparing physical activity behaviors from body motion using direct motion monitors (accelerometers) in 8 to 10 year old overweight and non-overweight children. We identified patterns of motion data to determine how and when children perform physical activity during a 7 day monitored period.  We then compared these patters of behavior among overweight, at risk of overweight, and non-overweight children to determine how active behaviors differ among these groups and which behaviors appeared specific to overweight children.
Role: Trainee

Measurement of Physical Activity in Obese and Non-obese Children

The Center for Self-Management Interventions for Populations at Risk (P30) Margaret Grey (PI)
Yale School of Nursing           %20,000          5/2003 – 6/2005          no salary support

The overall goal was to develop novel methods of describing and comparing physical activity behaviors from body motion using direct motion monitors (accelerometers) in 8 to 10 year old overweight and non-overweight children. We identified patterns of motion data to determine how and when children perform physical activity during a 7 day monitored period.  We then compared these patters of behavior among overweight, at risk of overweight, and non-overweight children to determine how active behaviors differ among these groups and which behaviors appeared specific to overweight children.
Role: Recipient of Pilot / Feasibility Award