Gerard Sanacora, MD, PhD
Associate Professor of Psychiatry Director, Yale Depression Research Program Research Interest

Mentee:

Jonas Hannestad

Dr. Sanacora’s work is focused largely on identifying the contributions of the amino acid neurotransmitter systems (GABA and Glutamate) to the neurobiology of mood disorders and the mechanism of antidepressant action. Specifically, his laboratory is employing novel magnetic resonance spectroscopy methodologies and pharmacological challenge paradigms to identify abnormalities in the function of the amino acid neurotransmitter systems in individuals suffering from mood and anxiety disorders. In addition, he is also using rodent models to further explore the effects of chronic stress on the physiology and molecular biology of the amino acid neurotransmitter systems, and to test novel treatment strategies targeting these systems.